The patient should closely monitored for prothrombin time (PT), who is already getting warfarin treatment initiated with oxandrolone therapy. The dose of warfarin adjusted or may have to be decreased as required until prothrombin time has been achieved. Patients should contact to doctor immediately if any bleeding sign is there including headache, weakness, pain, dizziness, nosebleeds, vaginal bleeding, increased menstrual flow, unusual bleeding or bruising, prolonged bleeding from cuts, red or brown urine, or red or black stools. Dicumarol and anisindione interaction with oxandrolone is same as warfarin.
Side effects compared to other substances are quite a bit weaker, the most frequently mentioned is acne and it has quite a strong influence on the digestive tract (at higher doses), . when taking Oxandrolone often mentioned is regular diarrhea. It is a 17 - alpha - alkylated preparation that is toxic to the liver, but not in extreme (studies where Oxandrolone was administered daily in amount of 20 mg for 12 weeks, minimal effect on increase in liver values was observed).
This substance in short and low use does not affect the endogenous production of testosterone. In prolonged use testicular atrophy is quite common. (The study has shown that over 12 weeks period of use of 80 mg daily suppresses endogenous testosterone production by 67%).