Injectable Primobolan (Methenolone Enanthate) as well as oral Primobolan (Methenolone Acetate) are both void of the typical C17-alpha alkylation common in nearly all oral anabolic steroids, and therefore Primobolan presents no measurable hepatotoxic effects on the body. Oral Primobolan has failed to demonstrate any changes in liver enzyme values that would be cause for concern. Primobolan in particular does possess in its own right a resistance to hepatic metabolism and breakdown, and only one incidence of a death resultant of hepatotoxicity and liver failure from oral Primobolan has been recorded in one male elderly individual who was prescribed the compound for the purpose of treating anemia. Therefore, higher doses of oral Primobolan can indeed be utilized but it must be noted that oral Primobolan does still possess a measure of resistance to metabolism and breakdown in the liver, and therefore the risk of hepatotoxicity from Primobolan must not be completely ignored, especially as doses of the oral format are increased to higher and higher amounts.
In a performance setting, Cytomel doses will be very similar to hypothyroidism treatment plans. The individual will normally begin with 25mcg per day and increase the total dose -25mcg every 2-4 weeks as needed. Most will find they will have no need to go above 75-100mcg per day, with the 125mcg per day range being acceptable for very short periods of time. Such a high dose might be acceptable at the end of a harsh contest diet but should not be a regular dose through the brunt of the diet. As for total use, 6-8 weeks will be the safest total duration. Longer can be acceptable, such as 8-12 weeks, but it does increase the risk of thyroid dependency. However, most healthy adults should not have an issue. Once you have reached your high end dose and it’s time to come off, you are encouraged to drop the dose down to 25mcg per day and hold at that dose for 7-10 days. This will allow the body to adjust and protect you from falling into hypothyroidism. For no reason should you discontinue use abruptly, the 7-10 day low dose is imperative.