Once more, an early study done on S-4 provided proof of full muscle regeneration in volunteers with with degenerative disorders without the use of exercise and the minimum dosage of 3mg/kg/day. Changes can be seen anywhere from 1-2 weeks. This was the very first study classified S-4 as CLINICALLY SIGNIFICANT by improving skeletal muscle strength, lean body mass, and a reduction in body fat [Chen et al., 2005; Gao et al., 2005; Kearbey et al., 2007]. Unfortunately, there are always some side effects that arise when using Because S-4 is a ligand by definition, the side effects will never be permanent even at supraphysiological dosages and can be easily avoided through proper dosing.
As an example, should you choose to run a cycle that includes both Dianabol and Anavar, you will need to be extremely careful when it comes to overlapping them. The two are both hepatotoxic, which means they will cause liver damage. You will need to consider this carefully when it comes to choosing cycle lengths. If you take Dianabol for four weeks at the beginning of your cycle, then make the switch to Anavar, you should limit your Anavar use to four weeks, as well. This reduces your entire cycle time to eight weeks, which helps to alleviate some of the risk of liver damage.
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